Dichloromethane is a member of the class of chloromethanes that is methane in which two of the hydrogens have been replaced by chlorine. Material safety data sheet educational innovations. Durable laminate that increases the label strength and resistance. Industrial, manufacturing or laboratory use manufacturer. Phe publications gateway number 2014790 pdf, 271kb, 14 pages this file may not be suitable for users of assistive technology. Chemical product and company identification product name. Acute toxicity is caused by cns depression, and fatalities have resulted from exposure. Other companies are charging thousands of dollars to set up accounts and give you access to their msds. Dichloromethane, at 50 mgl, had 0% degradation in a manometric respirometry test over a 28day incubation period9.
Toxicity to fish lc50 pimephales promelas fathead minnow 193. Dependable 3m adhesive vinyl that is built to resist harsh conditions. Your new online msds binder is a place for you to store the material safety data sheets you need to deploy. This chemicalproduct is not and cannot be distributed in commerce as defined in tsca section 35 or processed as defined in tsca section 3 for consumer paint or coating removal.
Safety data sheet methylene chloride page 4 issued. Standard operating procedure for halogenated solvents. Safety data sheet dichloromethane lrg according to regulation ec no 19072006, annex ii section 1. With these larger bottles attached your synthesizer can produce up to 40 average primerlength oligonucleotides with no. Details of the supplier of the safety data sheet 2. Dichloromethane has been shown to increase incidence of tumors in mice and rats. The occupational safety and health administrations osha hazard communication standard 29 cfr 1910. It is a colourless liquid with penetrating etherlike or mild sweet odour. This material is not expected to be harmful to aquatic life. With these larger bottles attached your synthesizer can produce up to 40 average primerlength oligonucleotides with no bottle changes, reducing a. This product is recommended for laboratory and manufacturing use only. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Dichloromethane 75092 reasonably anticipated to be a human carcinogen.
This hplc grade dichloromethane comes in a convenient large volume for abi 394 nucleic acid synthesizers, resulting in extended handsfree dna synthesis. Dichloromethane has been restricted since 1976 and it is currently restricted in annex iii entry 7 of the cosmetics directive 76768eec to a. Safety data sheet msds is obtained unless a current one is already. Extinguishing media which must not be used for safety reasons do not use water jet. Its utilization is as a solvent in manufacturing of fine chemicals, drugs, drug intermediates and pharmaceuticals, and also in food engineering. Dichloromethane skin rabbit 24h skin irritation eyes rabbit 24h mild eye irritation respiratory lc50 inhalation rat 52,000 mgm3 ingestion ld50 oral rat 2,000 mgkg methanol skin ld50 dermal rabbit 15,800 mgkg eyes eyes rabbit eye irritation 24 hour respiratory lc 50 rat 85 mgl, 4 hours lc 50 rat 64000.
Always wear recommended personal protective equipment. Material safety data sheet dichloromethane msds number. Human epidemiology studies did not shows a tumorigenic response. Sigmaaldrich 3050 spruce street saint louis mo 63103 usa telephone. Transportation information us dot un1593, dichloromethane, 6. Dichloromethane, hplc plus, for hplc, gc, and residue analysis. Special precautions, incompatiblereactive materials, usable shelf life, etc. Radchem cc po box 166982 brackendowns alberton 1454 telephone. Dichloromethane cas no 75092 material safety data sheet sds msds section 1. Safety data sheet dichloromethane bdh11 page 3 16 version 1. Safety data sheet northwest missouri state university. Methylene chloride mc means an organic compound with chemical formula.
Tested to withstand exposure to acetone, dichloromethane, hydrofluoric acid, and other tough chemicals and solvents. Extinguishing media suitable extinguishing media use water spray, alcoholresistant foam, dry chemical or carbon dioxide. Integrated risk information system iris november 2011. Original on 05222017 page 1 of 6 safety data sheet dichloromethane hplc 1. Special hazards arising from the substance or mixture. Martin, in pharmacology and therapeutics for dentistry seventh edition, 2017. Dichloromethane, otherwise known as methylene chloride, is a common solvent in paint remover and is used for liquidliquid extraction in laboratories. Dichloromethane is not believed to create a measurable carcinogenic risk to humans when handled correctly. Identification of the substancemixture and of the companyundertaking 1. Please ensure that this msds is given to, and explained to people using this product. Background dichloromethane is a synonym of methylene chloride and has the cas n 75092 and the ec n 2008389. Dichloromethane has been restricted since 1976 and it is currently restricted in annex iii entry 7 of the cosmetics directive 76768eec to a concentration of. Sds of dichloromethane, safety data sheets, cas 75092.
Sigmaaldrich d65100 page 3 of 6 parameters methylene chloride 75092 twa 50 ppm 20070101 usa. July 3, 2007 the dow chemical company page 4 of 7 epidemiological studies on more than 6,000 people exposed to methylene chloride in their workplace using over 35 years of observations showed no. Gb5001 page 1 of 7 fast setting joint compounds date. Methylene chloride, methylene dichloride, methylene bichloride, methane dichloride, dcm recommended use. However, we make no representation as to the comprehensiveness or accuracy of the info rmation. Product identifier product name dichloromethane lrg product number 1203 synonyms.
Material safety data sheet section 1 dichloromethane 1 chemical product and company identification msds name. Cornell university, planning design and construction, msds, dichloromethane accessed, march, 1999 environmental defense fund 1998, dichloromethane. It is the solvent of choice for caffeine extraction. It is employed as a solvent and paint remover, and as a blowing agent for polyurethane. P4methoxyphenylp4morpholinylphosphinodithioic acid, compound with morpholine 1. Do not allow product to contact skin, eyes and clothing. These sdss are designed to provide essential information.
Dichloromethane material safety data sheet cas no 75092. Other information revision b, june 2015 the information contained herein is provided in good faith and is believed to be correct as of the date hereof. Acgih threshold limit values tlv remarks central nervous system impairment carboxyhemoglobinemia substances for which there is a. Product identification name methylene chloride synonyms dichloromethane. Dichloromethane has been toxic to the fetus in in animals where the dose was toxic to the mother. En section 1 identification of the substance mixture and of the company undertaking product identifier product name dichloromethane chemical name methylene chloride. A dense, nonflammible colourless liquid at room temperature b. Methylene chloride dichloromethane 75092 30 60 xi 40 232425263 50 ppm 25 ppm 125 ppm all of the constituents of this adhesive product are listed on the tsca inventory of chemical substances maintained by the us epa, or are exempt from that listing. Safety data sheet a university in missouri, college in.
Safety data sheet methylene chloride page 3 issued. Dichloromethane methylene chloride, cas 75092 ghs chemical container label. Revised on 09262018 page 1 of 7 safety data sheet methanol 2% in dichloromethane 1. Phosgene may form in the head space in chloroform containers. July 3, 2007 the dow chemical company page 4 of 7 epidemiological studies on more than 6,000 people exposed to methylene chloride in their workplace using over 35 years of observations showed no increase in deaths from cancer or any other disease. This information includes the potential health effects of product exposure, hazards related to handling, storage or use, how to protect workers, and emergency protocol. Dichloromethane is employed in pharmaceutical applications. Cornell campus police 911 accidents, spills environmental health and safety 58200 gannett health center 55155 12. Hazard identification very hazardous in case of eye contact irritant, of ingestion, of inhalation. Methanol 2% in dichloromethane synonymsgeneric names. Methylene chloride dichloromethane 25ppm twa osha pel, 125 ppm stel 50 ppm twa acgih tlv 100 ppm twa uk oel, 300 ppm stel 75 ppm twa germany ags, 300 ppm stel soya lecithin none established in the united states, 29 cfr 1910.
443 229 398 346 1217 1342 1197 841 1163 1127 1407 1322 736 1486 212 626 197 777 440 1122 60 737 93 502 388 1168 421 761 819 438 863 1263 94 812 776